An axle is an axle. If the previously mentioned spring perches line up it will physically swap with no issues. The un seen concern would be the gear ratio. You'd want to be sure the ratio in the donar rear matches the front diff ratio from your 4x4.
I'm currently swapping a V6 8.25 drum brake axle for a V8 9.25 disc brake rear as a part of my HEMI swap.