Yes is the simple answer. Starting in I think 96, the trans' went from RH to RE and GenII Dakotas with the 5.2 seemed to have the 46RH. Bottom line though, GenIII Dak and GenI Dur were 3.9/5.2/5.9 with 42/44/46, respectively.
You'll also see 5-45RFE thrown around, the 45RFE and 5-45RFE are identical. The difference is programming that allows a second overdrive gear. Hemi Rams also use this transmission, among others...